Therapeutic potential of silymarin as a natural iron-chelating agent in β-thalassemia intermedia.

Abnormal iron accumulation in vital organs is one of the major complications of β-thalassemia intermedia (β-TI). Silymarin, a flavonolignan isolated from Silybum marianum, significantly decreases the serum ferritin levels of β-TI patients. This finding suggests silymarin as a safe and effective natural iron-chelating agent for the treatment of iron-overloaded conditions. © 2022 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd.

Citation

Nahid Reisi, Nafiseh Esmaeil, Marjan Gharagozloo, Behjat Moayedi. Therapeutic potential of silymarin as a natural iron-chelating agent in β-thalassemia intermedia. Clinical case reports. 2022 Jan;10(1):e05293

PMID: 35106163

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