The etiology and heterogeneity of idiopathic scoliosis (IS) are poorly understood. Studies using scoliotic zebrafish models have indicated a potential link between ciliary defects and scoliosis. They may further explain the onset of IS partially. However, it is necessary to further interpret the link between this progress and clinical medicine. Copyright © 2022 Elsevier Ltd. All rights reserved.
Ziyang Liu, Yong Hai, Zhuoran Li, Lingyun Wu. Zebrafish and idiopathic scoliosis: the 'unknown knowns'. Trends in genetics : TIG. 2022 Jun;38(6):524-528
PMID: 35115176
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