Neurological symptoms of hypomagnesemia].

Michel Cakici, Job van Steenkiste, Jan H Assink, Walid Moudrous

Nederlands tijdschrift voor geneeskunde 2021 Nov 25

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An epileptic seizure is a common neurological presentation in the Emergency Department (ED). Electrolyte disturbances are an important cause of neurological symptoms like seizures and hypomagnesemia is one of them. PPI's can cause hypomagnesemia and are readily prescribed. Therefore patients taking PPI's are at risk of developing neurological symptoms due to hypomagnesemia. A 82-year old woman was seen in ED with a history of nausea, vomiting and vertigo. A vertical nystagmus was observed with attacks of mydriasis followed by a phase of encephalopathy and restlessness. These were recognized as epilepsy. Hypokaliemia, hypocalcemia and a deep hypomagnesemia were present. The PPI accounted for hypomagnesemia. After 2 days of intravenous magnesium suppletion all symptoms disappeared. PPI's can cause hypomagnesemia and magnesium levels should be obtained in patients presenting with encephalopathy or atypical neurological symptoms.

Citation

Michel Cakici, Job van Steenkiste, Jan H Assink, Walid Moudrous. Neurological symptoms of hypomagnesemia]. Nederlands tijdschrift voor geneeskunde. 2021 Nov 25;165