Molecular characterization of methicillin-resistant Staphylococcus aureus genotype ST764-SCCmec type II in Thailand.

Methicillin-resistant Staphylococcus aureus (MRSA) is a significant causative agent of hospital-acquired infections. We characterized MRSA isolated from August 2012 to July 2015 from Thammasat University Hospital. Genotypic characterization of MRSA SCCmec type II and III isolates were scrutinized by whole genome sequencing (WGS). The WGS data revealed that the MRSA SCCmec type II isolates belonged to ST764 previously reported mainly in Japan. All of tested isolates contained ACME Type II', SaPIn2, SaPIn3, seb, interrupted SA1320, and had a virulence gene profile similar to Japan MRSA ST764. Rigorous surveillance of MRSA strains is imperative in Thailand to arrest its potential spread. © 2022. The Author(s).

Citation

Sumalee Kondo, Pimonwan Phokhaphan, Sissades Tongsima, Chumpol Ngamphiw, Worawich Phornsiricharoenphant, Wuthiwat Ruangchai, Areeya Disratthakit, Pholawat Tingpej, Surakameth Mahasirimongkol, Aroonlug Lulitanond, Anucha Apisarnthanarak, Prasit Palittapongarnpim. Molecular characterization of methicillin-resistant Staphylococcus aureus genotype ST764-SCCmec type II in Thailand. Scientific reports. 2022 Feb 08;12(1):2085

Mesh Tags

PMID: 35136112

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