Synthesis of aromatic lactone analogues of Lipoxin A4.

Synthesis of novel aromatic Lipoxin A4 lactone analogues. Novel para-substituted aromatic lactone analogues of Lipoxin A4 have been synthesized in a convergent manner with six steps in the longest linear sequence in 12-13% yields, employing 2-deoxy-D-ribose as a chiral pool starting material and the classical E-selective Wittig olefination. © 2022. The Author(s).

Citation

Aya Ismael, Muhammad Zeeshan, Jørn H Hansen. Synthesis of aromatic lactone analogues of Lipoxin A4. BMC research notes. 2022 Feb 09;15(1):30

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PMID: 35139886

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