Chemistry and biological evaluation of pyrido[4,3-d]pyrimidines: A review.

The aim of this review is to update the knowledge of different multi-component reactions that lead to synthesizing of pyrido[4,3-d]pyrimidines. In this study, the multiple synthetic pathways that are discussed in the synthesis of pyrido[4,3-d]pyrimidines lead are highlighted. Thus, the developed compounds have been derived from pyridine and pyrimidines fusion or from possible approaches of multistep synthesis reaction versatility. Apart from the synthetic schemes, their biological applications are also comprehended. This review discusses that the pyrido[4,3-d]pyrimidines have been developed by using new strategies and may be useful to future researchers. © 2022 John Wiley & Sons Ltd.

Citation

Pratibha Yadav, Kamal Shah. Chemistry and biological evaluation of pyrido[4,3-d]pyrimidines: A review. Chemical biology & drug design. 2022 May;99(5):758-768

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PMID: 35152554

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