Research Progress on Molecular Markers Related to Unexplained Sudden Cardiac Death and Its Forensic Application.

Xiang-Wang He, Lin-Feng Li, Fu Zhang, Li-Bing Yun

Fa yi xue za zhi 2021 Oct 25

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Routine pathological examination of unexplained sudden cardiac death (USCD) lacks significant morphological characteristics. In the field of forensic medicine, molecular biology methods have been used to find the cause of death by detecting genes and research related to the mechanism of sudden cardiac death has been carried out. From the molecular pathology point of view, the application of multiple levels of biomarkers to resolve the causes of USCD has already shown potential and provides an important path for forensic identification of USCD. This article reviews the latest research progress on USCD-related genes, RNA, proteins and USCD, and summarizes forensic application.

Citation

Xiang-Wang He, Lin-Feng Li, Fu Zhang, Li-Bing Yun. Research Progress on Molecular Markers Related to Unexplained Sudden Cardiac Death and Its Forensic Application. Fa yi xue za zhi. 2021 Oct 25;37(5):687-693