Junyi Chen, Longming Chen, Yahan Zhang, Liang Zhao, Ming Dong, Zhao Meng, Qingbin Meng, Chunju Li
Chemical communications (Cambridge, England) 2022 Mar 08The synthesis of the first water-soluble 2,2'',4,4''-terphen[3]arene bearing sulphonatopropoxy moieties (STP3) and its effective alleviation of aversive responses to alkaloids in vitro and in vivo, via the formation of supramolecular complexes, have been described. Using such direct host-guest complexation, STP3 has potential applications as an efficient taste-masking macrocyclic container for use in pharmaceutical research.
Junyi Chen, Longming Chen, Yahan Zhang, Liang Zhao, Ming Dong, Zhao Meng, Qingbin Meng, Chunju Li. The effective taste masking of alkaloids by a water-soluble terphen[3]arene. Chemical communications (Cambridge, England). 2022 Mar 08;58(20):3370-3373
PMID: 35191445
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