Praziquantel use in aquaculture - Current status and emerging issues.

Luke J Norbury, Sho Shirakashi, Cecilia Power, Barbara F Nowak, Nathan J Bott

International journal for parasitology. Drugs and drug resistance 2022 Apr

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Parasitic diseases are major constraints in fish mariculture. The anthelmintic praziquantel (PZQ) can effectively treat a range of flatworm parasites in a variety of fish species and has potential for broader application than its current use in the global aquaculture industry. In this review we report on PZQ's current use in the aquaculture industry and discuss its efficacy against various flatworm parasites of fish. Routes of PZQ administration are evaluated, along with issues related to palatability, pharmacokinetics and toxicity in fish, while PZQ's effects on non-target species, environmental impacts, and the development of drug-resistance are discussed. Copyright © 2022 The Author(s). Published by Elsevier Ltd.. All rights reserved.

Citation

Luke J Norbury, Sho Shirakashi, Cecilia Power, Barbara F Nowak, Nathan J Bott. Praziquantel use in aquaculture - Current status and emerging issues. International journal for parasitology. Drugs and drug resistance. 2022 Apr;18:87-102