Quercetin was described as an inhibitor of tyrosinase in an article published in Food Research International. However, it was firmly established in the literature before that this compound was a substrate of this enzyme and an antioxidant reducing tyrosinase-generated o-quinones. Copyright © 2022 Elsevier Ltd. All rights reserved.
Hubert Wojtasek. Quercetin is a substrate not an inhibitor of tyrosinase - comments on "Quercetin as a tyrosinase inhibitor: Inhibitory activity, conformational change and mechanism" published by Fan et al. (2017). Food research international (Ottawa, Ont.). 2022 Mar;153:110944
PMID: 35227469
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