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DNA ligase and PCNA: Double-ring down to seal a break in DNA.
Structure (London, England : 1993) 2022 Mar 03Sizes of these terms reflect their relevance to your search.
In this issue of Structure, Sverzhinsky et al. (2022) report structures of archaeal DNA ligase bound to the proliferating cell nuclear antigen (PCNA) sliding clamp and a nicked DNA substrate. The structures provide snapshots of ligation intermediates, which reveal a dynamic nature of the complex and explain how PCNA stimulates the DNA ligase activity. Copyright © 2022 Elsevier Ltd. All rights reserved.
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Hideki Aihara. DNA ligase and PCNA: Double-ring down to seal a break in DNA. Structure (London, England : 1993). 2022 Mar 03;30(3):324-326
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PMID: 35245433
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