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Cross-species microRNA transmission modulates flavivirus growth in mosquitoes.

Shwetha Shivaprasad, Peter Sarnow

Trends in parasitology 2022 May


filter terms:
  • chymotrypsin (1)
  • flavivirus (2)
  • human (2)
  • microrna (5)
  • mosquitoes (5)
  • mrna (1)
  • rna viruses (1)
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    Mosquitoes can be infected with a variety of RNA viruses. Recently,Zhu et al. demonstrated that human microRNA hsa-miR-150-5p is acquired by mosquitoes during blood meals and protects the Dengue virus by downregulation of chymotrypsin AaCT-1 mRNA. This finding suggests the use of microRNA antagomirs as an antiviral approach in mosquitoes. Copyright © 2022 Elsevier Ltd. All rights reserved.

    Citation

    Shwetha Shivaprasad, Peter Sarnow. Cross-species microRNA transmission modulates flavivirus growth in mosquitoes. Trends in parasitology. 2022 May;38(5):349-350

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    PMID: 35246384

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