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A genetic TRP down the channel to praziquantel resistance.

James A Cotton, Stephen R Doyle

Trends in parasitology 2022 May


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  • trp channel (1)
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    The anthelmintic praziquantel (PZQ) is an essential tool in controlling schistosomiasis, so reports of reduced PZQ efficacy are of great public health concern. Le Clec'h et al. recently identified a gene responsible for PZQ resistance in experimentally selected resistant Schistosoma mansoni. The importance of this locus in natural infections remains to be established. Copyright © 2022 Elsevier Ltd. All rights reserved.

    Citation

    James A Cotton, Stephen R Doyle. A genetic TRP down the channel to praziquantel resistance. Trends in parasitology. 2022 May;38(5):351-352

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    PMID: 35246385

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