MINERAL DENSITY OF BONE TISSUE AND METABOLIC INDICATORS IN CHILDREN WITH FRACTURES OF LONG BONES].

Objective - determine baseline bone mineral density in children and adolescents with low-energy fractures of long bones, assess vitamin D status. The data of densitometric and laboratory methods of investigation of 174 sick children with fractures of long bones at the age from 6 to 18 years were studied. Of these, there were 132 boys (75,9%), and 42 girls (24,1%). Bone mineral density (BMD) was assessed by the method of dual-energy X-ray absorptiometry on a DMS STRATOS bone densitometer (France) using the Eurasian regulatory database. Of 174 children with low-energy fractures of long bones, 97 patients were diagnosed with osteopenia, 19 - osteoporosis, and the remaining 58 patients had BMD values that corresponded to normal values. Low calcium levels in 46.2% of boys and 40.5% of girls, along with increased alkaline phosphatase activity in 90.2% of boys and 95.2% of girls, testified to impaired bone formation processes. When analyzing the content of vitamin D in the blood, 27.2% of boys and 28.6% of girls were found to be deficient, 63.7% of boys and 61.9% of girls were deficient, 3.8% of boys were severely deficient in vitamin D. At the same time, 5.3% of boys and 9.5% of girls had normal vitamin D values. Low bone mineral density, the presence of hypovitaminosis D in children and adolescents with low-energy fractures, given the importance of these indicators for fracture healing, require correction of the identified disorders: the choice of more sparing treatment methods, the appointment of adequate drug therapy, dynamic monitoring of the effectiveness of the prescribed therapy, and in children with a confirmed diagnosis of osteoporosis - studies of bone mineral density in dynamics.

Citation

F Umarov, Z Matanov. MINERAL DENSITY OF BONE TISSUE AND METABOLIC INDICATORS IN CHILDREN WITH FRACTURES OF LONG BONES]. Georgian medical news. 2022 Feb(323):89-93

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PMID: 35271477

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