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    Hypervirulent Klebsiella pneumoniae (hvKp) raised concern worldwide. We studied 22 hvKp clinical invasive isolates referred to the Belgian national reference laboratory between 2014 and 2020. Sixty-four percent of the isolates expressed K2 capsular serotype and belonged to 7 different MLST lineages, while 32% expressed K1 (all belonging to ST23) and were associated with liver abscesses. Primary extra-hepatic infections were reported in 36% and sepsis for 95% of the patients with 30% of deaths. Improved clinical and microbiological diagnostics are required as hvKp may represent an underestimated cause of community-acquired invasive infections in Belgium. © 2022. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.

    Citation

    Ahalieyah Anantharajah, Matthieu Deltombe, Marie de Barsy, Stephanie Evrard, Olivier Denis, Pierre Bogaerts, Marie Hallin, Véronique Yvette Miendje Deyi, Denis Pierard, Peggy Bruynseels, Jerina Boelens, Youri Glupczynski, Te-Din Huang. Characterization of hypervirulent Klebsiella pneumoniae isolates in Belgium. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology. 2022 May;41(5):859-865

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    PMID: 35353281

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