Pei Cao, Lei Zhang, Yang Yang, Xiao-Dan Wang, Zhao-Ping Liu, Jian-Wen Li, Li-Yuan Wang, Sookja Chung, Moqin Zhou, Ke Deng, Ping-Ping Zhou, Ping-Gu Wu
Food chemistry 2022 Sep 01The current study analysed concentrations of furan and its derivatives in coffee products commercially available in China based on an improved headspace gas chromatography-mass spectrometry (HS-GC-MS) method and estimated health risks. A total of 101 samples of coffee products on the Chinese market was analysed. Furan (98%, ND-6569 μg/kg) and 2-methylfuran (100%, 2-29639 μg/kg) were the compounds with the highest concentrations and detection rates in coffee products. The mean dietary exposure of Chinese consumers to furan and the sum of furan, 2-methylfuran and 3-methylfuran in coffee products was 0.09 and 0.46 μg/kg bw/day, respectively. For the neoplastic effects of furan, the margin of exposure (MOE) was 14,556 for the mean dietary exposure of consumers. For the non-neoplastic effects of furan, MOEs were 711 and 139 for furan and the sum of furan, 2-methylfuran and 3-methylfuran, respectively. Overall, a health concern is indicated for coffee consumers with MOEs below 10000. Copyright © 2022 Elsevier Ltd. All rights reserved.
Pei Cao, Lei Zhang, Yang Yang, Xiao-Dan Wang, Zhao-Ping Liu, Jian-Wen Li, Li-Yuan Wang, Sookja Chung, Moqin Zhou, Ke Deng, Ping-Ping Zhou, Ping-Gu Wu. Analysis of furan and its major furan derivatives in coffee products on the Chinese market using HS-GC-MS and the estimated exposure of the Chinese population. Food chemistry. 2022 Sep 01;387:132823
PMID: 35398680
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