Osteoimmunomodulatory effects of inorganic biomaterials in the process of bone repair].

Fei Xing, Qiyou Wu, Man Zhe, Rong Luo, Zhou Xiang, Ming Liu

Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery 2022 Apr 15

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To review the osteoimmunomodulatory effects and related mechanisms of inorganic biomaterials in the process of bone repair. A wide range of relevant domestic and foreign literature was reviewed, the characteristics of various inorganic biomaterials in the process of bone repair were summarized, and the osteoimmunomodulatory mechanism in the process of bone repair was discussed. Immune cells play a very important role in the dynamic balance of bone tissue. Inorganic biomaterials can directly regulate the immune cells in the body by changing their surface roughness, surface wettability, and other physical and chemical properties, constructing a suitable immune microenvironment, and then realizing dynamic regulation of bone repair. Inorganic biomaterials are a class of biomaterials that are widely used in bone repair. Fully understanding the role of inorganic biomaterials in immunomodulation during bone repair will help to design novel bone immunomodulatory scaffolds for bone repair.

Citation

Fei Xing, Qiyou Wu, Man Zhe, Rong Luo, Zhou Xiang, Ming Liu. Osteoimmunomodulatory effects of inorganic biomaterials in the process of bone repair]. Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery. 2022 Apr 15;36(4):517-522