Interdisciplinary Protocol for the Management of Vision-Threatening Papilledema.

Taylor Brady, Sravanthi Vegunta, Alison V Crum, Douglas Marx, Bhupendra C K Patel, Meagan D Seay, Richard H Schmidt, Judith E A Warner, Kathleen B Digre, Bradley J Katz

Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society 2022 Dec 01

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This study evaluates the effectiveness of a multidisciplinary protocol for management of patients with papilledema and vision loss secondary to increased intracranial pressure. Retrospective record review of all adult patients who presented with vision-threatening papilledema (VTPE) and were treated under this protocol. Patients are admitted for lumbar drain placement and diuretics and followed daily to determine if they may be managed medically or require surgery (optic nerve sheath fenestration [ONSF] and/or cerebrospinal fluid [CSF] shunting). Nineteen patients were included. Twelve had body mass index in the obese range and 6 were morbidly obese. Fourteen had idiopathic intracranial hypertension. Five had secondary pseudotumor cerebri syndrome related to medication use, dural venous sinus thro mbosis, hypothyroidism, end-stage renal disease, pulmonary disease, and diastolic heart failure. Three patients did not require surgery and were discharged on oral diuretics; 3 patients underwent unilateral ONSF, 9 underwent bilateral ONSF, and 4 underwent bilateral ONSF followed by ventriculoperitoneal shunt placement. The average follow-up was 10.1 months. The visual acuity improved bilaterally in 12 patients and unilaterally in 4 patients. The remaining 3 patients had worsened vision in both eyes. Fifteen patients had bilateral improvement in their visual fields. Five eyes in 3 patients showed further constriction of the visual field at follow-up. We demonstrate how a multidisciplinary complex care protocol for treating VTPE can expedite and streamline treatment and restore vision. We found that most patients had improved symptoms and signs, including visual acuity, visual fields, and papilledema. We encourage institutions that manage VTPE to adopt similar institutional protocols. Copyright © 2022 by North American Neuro-Ophthalmology Society.

Citation

Taylor Brady, Sravanthi Vegunta, Alison V Crum, Douglas Marx, Bhupendra C K Patel, Meagan D Seay, Richard H Schmidt, Judith E A Warner, Kathleen B Digre, Bradley J Katz. Interdisciplinary Protocol for the Management of Vision-Threatening Papilledema. Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society. 2022 Dec 01;42(4):495-501