Correlation Engine 2.0
Clear Search sequence regions

  • acid (3)
  • helminth proteins (2)
  • lipids (1)
  • nematoda (1)
  • plant (1)
  • protein family (1)
  • research (1)
  • retinol (6)
  • vitamin (2)
  • Sizes of these terms reflect their relevance to your search.

    Fatty acid-and retinol-binding proteins (FARs) belong to a unique family of excreted/secreted proteins (ESPs) found exclusively in nematodes. Much of our understanding of these proteins, however, is limited to their in vitro binding characteristics toward various fatty acids and retinol and has provided little insight into their in vivo functions or mechanisms. Recent research, however, has shown that FARs elicit an immunomodulatory role in plant and animal model systems, likely by sequestering lipids involved in immune signaling. This alludes to the intricate relationship between parasitic nematode effectors and their hosts.


    Sophia C Parks, Susan Nguyen, Martin J Boulanger, Adler R Dillman. The FAR protein family of parasitic nematodes. PLoS pathogens. 2022 Apr;18(4):e1010424

    Expand section icon Mesh Tags

    Expand section icon Substances

    PMID: 35446920

    View Full Text