Therapeutic strategies for treating juvenile idiopathic arthritis.

Melissa L Mannion, Randy Q Cron

Current opinion in pharmacology 2022 Jun

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Recent development of new medications has changed the juvenile idiopathic arthritis (JIA) treatment goal to inactive disease. With numerous options, how does a clinician choose which medication to use? Treatment options may depend on the clinical classification and a new paradigm considers the JIA subtypes in reference to categories of adult inflammatory arthritis; poligo JIA, spondyloarthritis JIA, and systemic JIA that can help guide a clinician in determining treatment options. Treatment strategies such as consensus treatment plans can provide guidance on treatment escalation. However, a treat-to-target strategy using frequent standardized disease activity measurements, shared decision making with the patient, and treatment escalation to achieve the disease activity target can provide a personalized approach to managing JIA. Copyright © 2022 Elsevier Ltd. All rights reserved.

Citation

Melissa L Mannion, Randy Q Cron. Therapeutic strategies for treating juvenile idiopathic arthritis. Current opinion in pharmacology. 2022 Jun;64:102226