Correlation Engine 2.0
Clear Search sequence regions


  • female (1)
  • heart failure (5)
  • humans (1)
  • patients (2)
  • sodium (1)
  • therapies (1)
  • Sizes of these terms reflect their relevance to your search.

    Abnormal fluid handling leads to physiologic abnormalities in multiple organ systems. Deranged hemodynamics, neurohormonal activation, excessive tubular sodium reabsorption, inflammation, oxidative stress, and nephrotoxic medications are important drivers of harmful cardiorenal interactions in patients with heart failure. Accurate quantitative measurement of fluid volume is vital to individualizing therapy for such patients. Blood volume analysis and pulmonary artery pressure monitoring seem the most reliable methods for assessing fluid volume and guiding decongestive therapies. Still the cornerstone of decongestive therapy, diuretics' effectiveness decreases with progression of heart failure. Extracorporeal ultrafiltration, an alternative to diuretics, has been shown to reduce heart-failure events. Copyright © 2021 Elsevier Inc. All rights reserved.

    Citation

    Maria Rosa Costanzo. The Cardiorenal Syndrome in Heart Failure. Cardiology clinics. 2022 May;40(2):219-235

    Expand section icon Mesh Tags

    Expand section icon Substances


    PMID: 35465896

    View Full Text