Bookmark
Forward
Synthesis of Substituted 2-Pyridones via 6π-Electrocyclization of Dienyl Isocyanates.
The Journal of organic chemistry 2022 May 06Sizes of these terms reflect their relevance to your search.
A one-pot Curtius rearrangement of dienyl carboxylic acids followed by a 6π-electrocyclization process to form substituted 2-pyridone products has been developed. Dienyl isocyanates generated from aliphatic acids were more reactive than their aromatic counterparts. Additionally, substitution patterns of the carboxylic acids had an impact on the efficiency of the cyclization.
Citation
Xiayun Cheng, Alexandria P Taylor, Kaicheng Zhu. Synthesis of Substituted 2-Pyridones via 6π-Electrocyclization of Dienyl Isocyanates. The Journal of organic chemistry. 2022 May 06;87(9):6403-6409
Mesh Tags
Substances
PMID: 35476425
View Full Text
