Li Ji, Leheng Zhang, Huiyi Yang, Shan Liang, Junkang Pan, Yikui Zou, Shijia Li, Qinglan Li, Suqing Zhao
Journal of colloid and interface science 2022 SepIn view of the current public health hazards of food-borne pathogens, it is urgent to develop a rapid detection method with high sensitivity, good specificity and operational convenience, as well as to determine an effective sterilization strategy. Herein, versatile gold-ruthenium nanocomposites modified with antibody (Au@Ru-pAb Ncs) have been constructed for the sensitive detection of Salmonella typhimurium (S. typhimurium) via the lateral flow immunochromatographic assay (LFIA). Au@Ru-pAb Ncs based LFIA exhibited a wide detection range from 2.9 × 106 CFU/mL to 2.9 × 1011 CFU/mL with the limit of detection of 9.8 × 104 CFU/mL for S. typhimurium, and displayed excellent specificity. In addition, Au@Ru-pAb Ncs irradiated with 808 nm (500 mW/cm2) near-infrared light (NIR) had a significant antibacterial effect within only 5 min, attributed to its high photothermal conversion efficiency of 54.14%. Therefore, both sensitive detection of S. typhimurium and effective NIR-triggered photothermal sterilization were achieved by using versatile Au@Ru-pAb Ncs, showing great prospects in the field of pathogen detection and treatment. Copyright © 2022 Elsevier Inc. All rights reserved.
Li Ji, Leheng Zhang, Huiyi Yang, Shan Liang, Junkang Pan, Yikui Zou, Shijia Li, Qinglan Li, Suqing Zhao. Versatile Au@Ru nanocomposites for the rapid detection of Salmonella typhimurium and photothermal sterilization. Journal of colloid and interface science. 2022 Sep;621:489-498
PMID: 35483180
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