Correlation Engine 2.0
Clear Search sequence regions

  • adult (2)
  • diagnosis (1)
  • humans (1)
  • hyponatremia (3)
  • patients (6)
  • serum (5)
  • sodium (5)
  • sodium level (2)
  • Sizes of these terms reflect their relevance to your search.

    The aim of the study was to investigate the predictive value of hyponatremia as a new biochemical marker for the early and accurate preoperative diagnosis of complicated appendicitis in the adult population. 732 patients who were operated for acute appendicitis (AA) and diagnosed as perforation intraoperatively were evaluated retrospectively. Serum sodium, C-reactive protein (CRP), and leukocyte levels of patients with perforated and nonperforated appendicitis were compared. Perforated appendicitis patients had statistically lower serum Na values (p<0.001). Similarly, patients without perforated appendicitis had higher serum CRP values (p<0.001). In patients diagnosed with perforated AA, the sensitivity of plasma sodium concentration was 63%, and the specificity was 66%. The threshold value of plasma sodium concentration ≤137.5 mEq/L had the best possible sensitivity and specificity. Hyponatremia is a new marker of perforated appendicitis and therefore, serum sodium level measurement should be considered in patients with a clinical presentation consistent with appendicitis if complications are suspected.


    Veysel Barış Turhan, Abdulkadir Ünsal, Bülent Öztürk, Doğan Öztürk, Hakan Buluş. Predictive value of serum sodium level in determining perforated appendicitis. Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES. 2022 Mar;28(3):290-295

    Expand section icon Mesh Tags

    Expand section icon Substances

    PMID: 35485569

    View Full Text