A case of autopsy discovery of acute chest syndrome triggered by pulmonary embolism in a sickle cell patient.

Kouadio Marc-Eric Victor Ebouat, Zana Konate, Zié Moussa Coulibaly, Mathurin Djodjo, Koffi Botti, Hélène Yapo-Etté

Forensic science, medicine, and pathology 2022 Sep

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This is a case report about a 7-year-old male child with sickle cell anemia (S/β+) who died unexpectedly during hospitalization, justifying the performance of a forensic autopsy completed by histological examination of organ fragments and toxicological analyses of biological fluids. The diagnosis retained was pulmonary thromboembolism as the cause of death occurring in the context of an acute chest syndrome (ACS). The mechanism of occurrence of this pulmonary embolism was vascular stasis caused by sickle cell disease. The search for etiologies of ACS complicating sickle cell disease should not exclude pulmonary embolism with red cell dense fibrin clot.. © 2022. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

Citation

Kouadio Marc-Eric Victor Ebouat, Zana Konate, Zié Moussa Coulibaly, Mathurin Djodjo, Koffi Botti, Hélène Yapo-Etté. A case of autopsy discovery of acute chest syndrome triggered by pulmonary embolism in a sickle cell patient. Forensic science, medicine, and pathology. 2022 Sep;18(3):251-255