Silyl formates as hydrosilane surrogates for the transfer hydrosilylation of ketones.

R Martin Romero, Neethu Thyagarajan, Nora Hellou, Clément Chauvier, Timothé Godou, Lucile Anthore-Dalion, Thibault Cantat

Chemical communications (Cambridge, England) 2022 May 03

filter terms:

A transfer hydrosilylation of ketones employing silyl formates as hydrosilane surrogates under mild conditions is presented. A total of 24 examples of ketones have been successfully converted to their corresponding silyl ethers with 61-99% yields in the presence of a PNHP-based ruthenium catalyst and silyl formate reagent. The crucial role of the ligand for the transformation is demonstrated.

Citation

R Martin Romero, Neethu Thyagarajan, Nora Hellou, Clément Chauvier, Timothé Godou, Lucile Anthore-Dalion, Thibault Cantat. Silyl formates as hydrosilane surrogates for the transfer hydrosilylation of ketones. Chemical communications (Cambridge, England). 2022 May 03;58(43):6308-6311