Enzyme replacement therapy leading to improvement in myeloma indices in a patient with concomitant Gaucher disease.

Reut Harel, Israel Gavish, Ariel Aviv, Nofar Greenman Maravi, Philippe Trougouboff, Ari Zimran, Shoshana Revel-Vilk

Internal medicine journal 2022 May

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Patients with Gaucher disease (GD) have been shown previously to carry an increased risk for cancer, most commonly multiple myeloma (MM). It is currently unknown whether treatment for GD has an effect on the prevention or amelioration of MM. We present the case of a 41-year-old patient simultaneously diagnosed with GD and smouldering MM. Enzyme replacement therapy with Velaglucerase-alfa significantly improved myeloma indices. © 2022 Royal Australasian College of Physicians.

Citation

Reut Harel, Israel Gavish, Ariel Aviv, Nofar Greenman Maravi, Philippe Trougouboff, Ari Zimran, Shoshana Revel-Vilk. Enzyme replacement therapy leading to improvement in myeloma indices in a patient with concomitant Gaucher disease. Internal medicine journal. 2022 May;52(5):872-875