Linderasesterterpenoids A and B: Two 7-Cyclohexyldecahydroazulene Carbon Skeleton Sesterterpenoids Isolated from the Root of Lindera glauca.

Zelin Chen, Xiaocong Chen, Yuqian Tang, Yuwei Zhou, Huimei Deng, Jingxin He, Yena Liu, Zhongxiang Zhao, Hui Cui

Organic letters 2022 May 27

filter terms:

Two novel sesterterpenoids linderasesterterpenoids A (1) and B (2) with an unprecedented 7-cyclohexyldecahydroazulene carbon skeleton isolated from the root of Lindera glauca. Their structures were elucidated by X-ray diffraction, quantum chemical calculations, and spectroscopic methods. The biogenetic pathway for 1 and 2 is proposed. In the bioassay, linderasesterterpenoids A and B showed good inhibitory activities against LPS-induced NO production in RAW 264.7 cells compared to a positive control.

Citation

Zelin Chen, Xiaocong Chen, Yuqian Tang, Yuwei Zhou, Huimei Deng, Jingxin He, Yena Liu, Zhongxiang Zhao, Hui Cui. Linderasesterterpenoids A and B: Two 7-Cyclohexyldecahydroazulene Carbon Skeleton Sesterterpenoids Isolated from the Root of Lindera glauca. Organic letters. 2022 May 27;24(20):3717-3720