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    The evaluation of chemicals for their carcinogenic hazard requires the analysis of a wide range of data and the characterization of these results relative to the key characteristics of carcinogens. The workflow used historically requires many manual steps that are labor-intensive and can introduce errors, bias and inconsistencies. The automation of parts of the evaluation workflow using the kc-hits software has led to significant improvements in process efficiency, as well as more consistent and comprehensive results. Supplementary data are available at Bioinformatics online. © The Author(s) 2022. Published by Oxford University Press. All rights reserved. For permissions, please e-mail:


    Brad Reisfeld, Aline de Conti, Fatiha El Ghissassi, Lamia Benbrahim-Tallaa, William Gwinn, Yann Grosse, Mary Schubauer-Berigan. kc-hits: a tool to aid in the evaluation and classification of chemical carcinogens. Bioinformatics (Oxford, England). 2022 May 13;38(10):2961-2962

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    PMID: 35561175

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