Subungual Pigmented Squamous Cell Carcinoma in a Dog.

Yeseul Yang, Du-Min Go, Jae-Ha Jung, Dansong Seo, Sung-Hyun Hwang, Mijung Lee, Dae-Yong Kim, Yongbaek Kim

Journal of comparative pathology 2022 Jun

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An 11-year-old spayed female Miniature Schnauzer dog was presented with loss of a claw caused by a nail bed mass. Histopathological evaluation revealed that the mass comprised neoplastic squamous cells with abundant cytoplasmic melanin pigment. Immunohistochemically, the neoplastic cells were positive for cytokeratin and negative for vimentin and ionized calcium-binding adaptor molecule 1, supporting a diagnosis of pigmented squamous cell carcinoma. To our knowledge, this is the first report of subungual pigmented squamous cell carcinoma in animals. Copyright © 2022 Elsevier Ltd. All rights reserved.

Citation

Yeseul Yang, Du-Min Go, Jae-Ha Jung, Dansong Seo, Sung-Hyun Hwang, Mijung Lee, Dae-Yong Kim, Yongbaek Kim. Subungual Pigmented Squamous Cell Carcinoma in a Dog. Journal of comparative pathology. 2022 Jun;194:50-53