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Sporadic Creutzfeldt-Jakob disease (sCJD) is a rare transmissible disease. According to molecular classification, six clinical phenotypes of sCJD have been described: MM1, MM2, MV1, MV2, VV1 and VV2. MV2 subtype comprises 9% of sCJD cases. Atypical clinical course has been reported to be the main caveat for the diagnosis of the MV2 subtype. We hereby present a rare case of MV2 subtype of sCJD, highlighting the evolution of clinical, EEG and imaging attributes over a two-year period, thus underlining the atypical course of the disease.


Afrantou Theodora, Syntila Styliani-Aggeliki, Ioannidis Panagiotis, Sklaviadis Theodoros, Boziki Marina, Grigoriadis Nikolaos. EEG - Imaging Evolution of the MV2 Subtype of Sporadic Creutzfeldt-Jakob Disease During the two-Year Course of the Disease. Clinical EEG and neuroscience. 2023 Mar;54(2):164-167

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PMID: 35585697

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