Interferon α-induced lupus-like reaction in a mycosis fungoides patient: A case report.

Farahnaz Fatemi Naeini, Maral Yazdanpanah, Fatemeh Mohaghegh, Parvin Rajabi, Elham Tavousi Tabatabaei

International journal of clinical pharmacology and therapeutics 2022 Jul

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Mycosis fungoides (MF) is the most common form of cutaneous T-cell lymphomas and interferon α is one of the treatment modalities for MF patients. So far, various side effects have been reported in connection with interferon use, including lupus-like reaction, which is relatively rare and classified as an injection-site reactions (ISR). We report a 38-year-old female with history of MF for 2 years who developed cutaneous lesions at the sites of interferon α-2b injections. There are few reports of lupus-like reaction due to therapy with interferon in malignant melanoma and multiple sclerosis (MS) patients, but there is no report in the literature about this side effect among patients with MF.

Citation

Farahnaz Fatemi Naeini, Maral Yazdanpanah, Fatemeh Mohaghegh, Parvin Rajabi, Elham Tavousi Tabatabaei. Interferon α-induced lupus-like reaction in a mycosis fungoides patient: A case report. International journal of clinical pharmacology and therapeutics. 2022 Jul;60(7):306-310