Correlation Engine 2.0
Clear Search sequence regions

  • arthroplasty (1)
  • bone (6)
  • bone bone (1)
  • donor (1)
  • fraction cells (2)
  • marrow (7)
  • talus (1)
  • titanium (7)
  • Sizes of these terms reflect their relevance to your search.

    Red bone marrow and autologous bone tissue (bone fragments and bone chips) of the donor were harvested intraoperatively during autoplasty of talus bone defect. Titanium chips were obtained by grinding a fragment of a microporous titanium-coated hip arthroplasty (Zimmer). Bone marrow mononuclear cells were isolated in the operating room, and bone and titanium fragments were incubated with a suspension of mononuclear cells. The quality of revitalization was assessed by fluorescence microscopy and histological examination after culturing of adherent cells on the bone and titanium fragments. During culturing on bone chips, bone marrow mononuclear fraction cells demonstrated significantly higher metabolic activity than bone marrow cells (p=0.04). Mononuclear fraction cells were also capable of stable colonization of titanium fragments with the formation of composite tissue model. © 2022. Springer Science+Business Media, LLC, part of Springer Nature.


    D S Baranovskii, B G Akhmedov, A G Demchenko, M E Krasheninnikov, M V Balyasin, O Yu Pavlova, N S Serova, O A Krasil'nikova, P V Shegai, A D Kaprin, I D Klabukov. Minimally Manipulated Bone Marrow-Derived Cells Can Be Used for Tissue Engineering In Situ and Simultaneous Formation of Personalized Tissue Models. Bulletin of experimental biology and medicine. 2022 May;173(1):139-145

    Expand section icon Mesh Tags

    Expand section icon Substances

    PMID: 35622254

    View Full Text