SARS-CoV-2 Virology.

Yijia Li, Jonathan Z Li

Infectious disease clinics of North America 2022 Jun

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Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first identified in 2020 and has led to an unprecedented global pandemic. Understanding the virology behind SARS-CoV-2 infection has provided key insights into our efforts to develop antiviral agents and control the COVID-19 pandemic. In this review, the authors focus on the genomic features of SARS-CoV-2, its intrahost and interhost evolution, viral dynamics in respiratory tract, and systemic dissemination. Copyright © 2022 Elsevier Inc. All rights reserved.