Non-human primates in prion diseases.

Emmanuel E Comoy, Jacqueline Mikol, Jean-Philippe Deslys

Cell and tissue research 2023 Apr

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The fascinating history of prion diseases is intimately linked to the use of nonhuman primates as experimental models, which brought so fundamental and founding information about transmissibility, pathogenesis, and resistance of prions. These models are still of crucial need for risk assessment of human health and may contribute to pave a new way towards the moving field of prion-like entities which now includes the main human neurodegenerative diseases (especially Alzheimer's and Parkinson's diseases). © 2022. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.