Structural elements of bactopterin from Pseudomonas carboxydoflava carbon monoxide dehydrogenase.

B Krüger, O Meyer

Biochimica et biophysica acta 1987 Apr 30

filter terms:

Bactopterin is a novel pterin occurring in bacterial molybdoenzymes as the organic portion of the molybdenum cofactor. Its structure is investigated here. The compound contains a single pterin ring and carries a side chain at carbon atom 6 of the pterin nucleus as indicated by the formation of pterin-6-carboxylic acid upon alkaline permanganate oxidation. Studies with phosphate-cleaving enzymes revealed the presence of two monophosphoric acid monoesters. The affinity of reduced bactopterin for thiol-Sepharose points to the presence of thiol(s) in active bactopterin.

Citation

B Krüger, O Meyer. Structural elements of bactopterin from Pseudomonas carboxydoflava carbon monoxide dehydrogenase. Biochimica et biophysica acta. 1987 Apr 30;912(3):357-64