Research Progress of Liujunzi Decoction in the Treatment of Tumor-Associated Anorexia.

Xipei Wu, Yongzhao Dai, Ke Nie

Drug design, development and therapy 2022

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Tumor-associated anorexia, mainly including cancerous anorexia and chemotherapy-induced anorexia, severely reduces the life quality of cancer patients but lacks of effective control until now. Liujunzi decoction (LJZD), a classical tonifying formula in traditional Chinese medicine, has promising effect in preventing and treating many kinds of anorexia. A growing number of evidence showed that LJZD is able to improve tumor-associated anorexia. Up to March 2022, a total of 58 articles studying LJZD or Rikkunshito (the name of LJZD in Japanese herbal medicine) in the treatment of tumor-associated anorexia are searched out in PubMed. This paper summarizes the effect of LJZD in ameliorating tumor-associated anorexia, in order to provide a theoretical basis for the clinical application of LJZD in treating tumor-associated anorexia, laying foundation for further research. © 2022 Wu et al.

Citation

Xipei Wu, Yongzhao Dai, Ke Nie. Research Progress of Liujunzi Decoction in the Treatment of Tumor-Associated Anorexia. Drug design, development and therapy. 2022;16:1731-1741