Fibroblast Activation Protein Inhibitor Theranostics.

Shobhana Raju, Jaya Shukla, Rakesh Kumar

PET clinics 2022 Jul

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The evolution of the fibroblast activation protein inhibitor molecules over the past decade has brought into the forefront a novel theranostic agent that has the potential of matching the workhorse of PET/computed tomography, [fluorine-18] fluoro-2-deoxy-d-glucose (18F-FDG). It is hoped that in the next decade it can act as a complementary tracer to 18F-FDG, in providing phenotypic and biomarker information and also in directing fibroblast activation protein-targeted therapies. Copyright © 2022 Elsevier Inc. All rights reserved.