Surgical management of Graves' disease: historical context and single institution experience.

Michael J Russell, Simon Young, Richard Martin, Richard Harman

The New Zealand medical journal 2022 Feb 04

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To describe indications and outcomes of total thyroidectomy for Graves' disease in a large New Zealand endocrine surgery unit, and to compare these results to international studies. We analysed a prospectively collected database to describe the indications and outcomes of surgery for Graves' disease between December 2001 and January 2021. Among 64 patients who underwent total thyroidectomy at our tertiary centre for Graves' hyperthyroidism, Graves' ophthalmopathy and patient preference/aversion to radioactive iodine were the most common indications for surgery. Total thyroidectomy resulted in long-term control of thyrotoxicosis in all patients. There were no incidences of recurrent laryngeal nerve injury. One patient (1.6%) suffered permanent hypoparathyroidism. Total thyroidectomy is a safe and effective treatment for Graves' disease. In our population, total thyroidectomy functions as a second-line treatment for Graves' disease.

Citation

Michael J Russell, Simon Young, Richard Martin, Richard Harman. Surgical management of Graves' disease: historical context and single institution experience. The New Zealand medical journal. 2022 Feb 04;135(1549):43-49