Correlation Engine 2.0
Clear Search sequence regions

  • isomers (4)
  • nitrogen (5)
  • Sizes of these terms reflect their relevance to your search.

    Differentiation of heterocyclic isomers by solution 1H, 13C, and 15N NMR spectroscopy is often challenging due to similarities in their spectroscopic signatures. Here, 13C{14N} solid-state NMR spectroscopy experiments are shown to operate as an "attached nitrogen test", where heterocyclic isomers are easy to distinguish based on one-dimensional nitrogen-filtered 13C solid-state NMR. We anticipate that these NMR experiments will facilitate the assignment of heterocyclic isomers during synthesis and natural product discovery.


    Rick W Dorn, Brendan J Wall, Sarah B Ference, Sean R Norris, Joseph W Lubach, Aaron J Rossini, Brett VanVeller. Attached Nitrogen Test by 13C-14N Solid-State NMR Spectroscopy for the Structure Determination of Heterocyclic Isomers. Organic letters. 2022 Aug 12;24(31):5635-5640

    Expand section icon Mesh Tags

    Expand section icon Substances

    PMID: 35731042

    View Full Text