Use of prophylactic phototherapy for RhD neonatal disease in a referral service.

This study aimed to describe the effect of prophylactic phototherapy in the treatment of infants with Neonatal Hemolytic Disease. A retrospective cohort study was carried out with 199 RhD-positive infants, born to RhD-negative mothers, alloimmunized for RhD antigen, between January 2009 and December 2018. The incidence of exchange transfusions in the study population was 9.5%, with a mean maximum bilirubin value of 11.3 mg % (± 4.3mg %). Bilirubin's maximum peak was achieved with a mean of 119.2 life hours (± 70.6h). The low incidence of exchange transfusion, the extended maximum bilirubin peak for later ages, and the low mean of the maximum bilirubin values may indicate a positive effect of prophylactic phototherapy in the treatment of this disease. Further studies must be carried out to confirm these findings. Copyright © 2022 Sociedade Brasileira de Pediatria. Published by Elsevier Editora Ltda. All rights reserved.

Citation

Joyce Marques da Silva Robalinho Rodrigues, Maria Dalva Barbosa Baker Méio, Maria Cristina Pessoa Dos Santos, Ana Carolina Carioca da Costa, Maria Elisabeth Lopes Moreira. Use of prophylactic phototherapy for RhD neonatal disease in a referral service. Jornal de pediatria. 2023 Jan-Feb;99(1):53-58

Mesh Tags

Substances

PMID: 35752322

search → result