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In the last recent years, the introduction in the clinical setting of treatment combinations having immune checkpoint inhibitors as the backbone has dramatically improved the outcomes of patients suffering from advanced/metastatic renal cell carcinoma (RCC). Here we report the clinical course of a patient with a rapid and bulky bone recurrence of RCC after nephrectomy, experiencing long-term benefit from nivolumab-ipilimumab administered as first-line treatment.


Marilena Di Napoli, Carmela Pisano, Sergio Venanzio Setola, Sisto PerdonĂ , Florinda Feroce, Sandro Pignata. Nivolumab-ipilimumab in renal cell carcinoma metastatic to the bones: A case report. Acta bio-medica : Atenei Parmensis. 2022 Jun 29;93(S1):e2022132

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PMID: 35765962

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