Aneuploidy is relatively common in mammalian preimplantation embryos, due to chromosome segregation errors in mitosis. A new paper in Development investigates whether the mitotic timer mechanism, a checkpoint that detects prolonged M phase, which may indicate an unhealthy cell division, is active in preimplantation mouse embryos. We caught up with first author Adélaïde Allais and corresponding author Greg FitzHarris (Professor at the Université de Montréal) to find out more about their research. © 2022. Published by The Company of Biologists Ltd.
The people behind the papers - Adélaïde Allais and Greg FitzHarris. Development (Cambridge, England). 2022 Jul 01;149(13)
PMID: 35771636
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