Correlation Engine 2.0
Clear Search sequence regions

  • chyle (4)
  • chylothorax (7)
  • diagnosis (1)
  • female (1)
  • food (1)
  • humans (1)
  • infant (8)
  • infant formula (2)
  • learn (1)
  • milk human (13)
  • patients (1)
  • term infants (1)
  • weight (2)
  • weight gain (4)
  • Sizes of these terms reflect their relevance to your search.

    To learn how skimmed human milk (SHM) can be used in infants with chylothorax to support adequate weight gain and nutrition while receiving human milk. Traditional nutrition management for chylothorax is to limit long-chain triglycerides (LCTs) and provide a diet high in medium-chain triglycerides (MCTs). Transition from human milk to formula has been required to provide the ratio of MCT to LCT required to stop the accumulation of chyle. Although SHM may provide the right fat content for a baby with chylothorax, previous studies have shown slow growth in infants receiving SHM. To demonstrate that infants receiving SHM fortified with high-MCT infant formula will have age appropriate growth without re-accumulation of chyle. Between 2017 and 2019, term infants with the diagnosis of chylothorax who were previously receiving human milk and transitioned to fortified SHM were monitored for growth and reaccumulation of chyle. The six infants who were prescribed fortified SHM with high-MCT infant formula using standardized recipes did not show reaccumulation of chyle and showed positive weight gain in five of the six study patients. The infants gained a mean weight of 30.5 g/day (±19.5), and their weight z scores improved by a mean of +0.29 (±0.33). Fortified SHM is a safe treatment option that can provide adequate nutrition for the infant with chylothorax to gain weight appropriately for age. © 2022 American Society for Parenteral and Enteral Nutrition.


    Brittani Clark, Melissa Froh, Catherine Karls, Mary Beth Feuling, Praveen Goday, Michael Uhing, Stephanie S Handler, T Hang Nghiem-Rao, Elizabeth Polzin. Assessing growth of infants with chylothorax receiving fortified skimmed human breast milk. Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition. 2023 Feb;38(1):199-203

    Expand section icon Mesh Tags

    Expand section icon Substances

    PMID: 35780315

    View Full Text