Potential intravenous immunoglobulin-induced optic disc edema.

To report a case of recurrent and bilateral optic disc edema following intravenous immunoglobulin (IVIG) administration. A 46 year-old woman received IVIG on 3 separate occasions over 7 years for Non-Hodgkin's Lymphoma (NHL) and each time developed headaches and transient visual disturbance, and was subsequently found to have bilateral optic disc swelling. Lumbar puncture confirmed raised cerebrospinal fluid (CSF) opening pressure and there was resolution following treatment with oral acetazolamide (Diamox). To our knowledge there is no literature on papilledema following administration of IVIG. This case is pertinent for physicians treating patients with IVIG who develop headache, transient visual disturbance and optic disc edema. © 2022 The Authors.

Citation

Anna K Britton, Anagha Vaze, Sam Milliken, Clare L Fraser. Potential intravenous immunoglobulin-induced optic disc edema. American journal of ophthalmology case reports. 2022 Sep;27:101617

PMID: 35789798

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