Orbital Metastasis: A Rare but Typical Location of Small Intestine Neuroendocrine Tumor on 18F-FDOPA PET/CT.

David Morland, Lucas Jallet, Sophie Deguelte, Guillaume Cadiot, Dimitri Papathanassiou

Clinical nuclear medicine 2022 Aug 01

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Orbital foci of increased uptake are sometimes visualized on 18F-FDOPA PET/CT, but the literature remains poor as to their nature. The orbit is indeed a rare site of metastatic involvement. Given this low probability of metastatic location, the question of an incidental benign finding may arise. We reviewed all 18F-FDOPA PET/CT examinations performed at our institution between January 2015 and May 2021: 4/149 patients presented at least 1 orbital focus of increased uptake, all of them presented a metastatic small intestine neuroendocrine tumor. Somatostatin receptor expression was confirmed using 68Ga-DOTATOC PET/CT supporting the hypothesis of genuine metastases. Copyright © 2022 Wolters Kluwer Health, Inc. All rights reserved.

Citation

David Morland, Lucas Jallet, Sophie Deguelte, Guillaume Cadiot, Dimitri Papathanassiou. Orbital Metastasis: A Rare but Typical Location of Small Intestine Neuroendocrine Tumor on 18F-FDOPA PET/CT. Clinical nuclear medicine. 2022 Aug 01;47(8):717-718