A new study uses reconstituted, functional octameric exocyst complex to provide new insights into the assembly of this tethering complex and reveal how the activity of the lipid kinase PIP5K1C stimulated by Arf6 on exocytic vesicles allows for exocyst-mediated tethering at the plasma membrane. Copyright © 2022 Elsevier Inc. All rights reserved.
Lars Langemeyer, Christian Ungermann. Vesicle transport: Exocyst follows PIP2 to tether membranes. Current biology : CB. 2022 Jul 11;32(13):R748-R750
PMID: 35820387
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