Evaluation of resistance to radial cyclic loads of poly(L-lactic acid) braided stents with different braiding angles.

Poly(L-lactic acid) (PLLA) braided stents have superior biocompatibility and flexibility, substituting metal stents in peripheral blood vessels. However, the radial supporting capacity of PLLA braided stent should be improved to bear the dynamic load from the peripheral artery. This paper evaluated the radial support performance of PLLA braided stents with different braiding angles after the radial cyclic loads test. The results indicate that braiding angle of stents is an important parameter affecting its ability to resist radial cyclic loads. The stent with a smaller braiding angle has better initial radial support but insufficient durability, while the stent with a larger braiding angle could maintain adequate radial support and suitable ability to resist radial cyclic loads. The theoretical analysis, verified by observing the surface morphology of filament crossover points, found that filaments of the stents with smaller braiding angles have more significant axial displacement and axial rotation angle during radial compression, which made the friction phenomenon more intense and led to insufficient ability to resist radial cyclic loads. This study could provide a meaningful idea for preparing biodegradable braided stents with suitable ability to resist radial cyclic loads. Copyright © 2022 Elsevier B.V. All rights reserved.

Citation

Qingwei Liu, Muqing Liu, Yuan Tian, Jie Cheng, Ji Lang, Yi Zhang, Gutian Zhao, Zhonghua Ni. Evaluation of resistance to radial cyclic loads of poly(L-lactic acid) braided stents with different braiding angles. International journal of biological macromolecules. 2022 Oct 01;218:94-101

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PMID: 35870623

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