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A 23-year-old female complained of excessive wrinkling of her hands after brief exposure to water. The symptoms were characteristic for the diagnosis aquagenic wrinkling of the palms (AWP). This disorder is frequently associated with cystic fibrosis (CF) or CF carrier state. DNA analysis of the cystic fibrosis gene is indicated.

Citation

Jonathan W J Melger, Patricia J C Knijnenburg, Inge B Mathijssen. A female with excessive wrinkling of the hands]. Nederlands tijdschrift voor geneeskunde. 2022 May 09;166

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PMID: 35899726

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