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The aim: To establish the dynamics of changes in the average total diameter, the diameter of the lumen of microvessels in the cortex of the rats' adrenal glands influenced by the long-term action food additives complex. Materials and methods: To determine the structural changes of the vessels of the hemomicrocirculatory bed of the cortex of the adrenal glands of rats in our study, we used histological, morphometric and statistical methods. Results: During the study, we found that the effect of a food additive complex on the vessels of the adrenal glands cortex of rats leads to a violation of hemodynamic conditions in the early stages of the experiment. Conclusions: arterioles, venules and capillaries as a capacitive link of the hemomicrocirculatory bed are actively involved in response to exogenous administration of a complex of food additives (sodium glutamate, sodium nitrite, and ponso 4 R). Processes of change of morphometric indicators of vessels are observed mainly from the fourth week of the experiment.


Serhii M Bilash, Svitlana V Donchenko, Olena M Pronina, Mykhailo M Koptev, Yaryna O Oliinichenko, Valentyna V Onipko, Volodymyr I Ischenko. MORPHOMETRIC FEATURES OF THE ELEMENTS OF THE HEMOMICROCIRCULATORY BED IN THE CORTEX OF THE ADRENAL GLANDS INFLUENCED BY THE FOOD ADDITIVES COMPLEX. Wiadomosci lekarskie (Warsaw, Poland : 1960). 2022;75(6):1558-1563

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PMID: 35907234

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